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INTRACRANIAL
ANEURYSMS: Frequently Asked Questions (FAQs)
Presented
by Terry G. Horner, MD
Neurosurgeon with Indianapolis Neurosurgical Group, Inc.
ING
Video: Strokes
and Aneurysms
Frequently
Asked Questions (Aneurysms): Click on the question for the answer.
What
is an intracranial aneurysm?
An aneurysm is a ballooning out of the wall of a blood vessel. In the
brain, an aneurysm usually arises at a branch in the blood vessel. The
reason aneurysms develop is not completely understood. There is an absence
of one of the layers in the wall of the blood vessel, which may have been
absent since birth. Degenerative changes in the blood vessel wall occur
with aging and may also contribute to the formation of an aneurysm.
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Who
gets aneurysms?
Women are affected more frequently than men are. Smoking is a risk factor.
Although aneurysms may develop in young people, they most commonly occur
between the ages of 40 to 70 years. People with certain diseases such
as polycystic kidney disease, Marfan’s syndrome, or coarctation
of the aorta are more likely to develop intracranial aneurysms.
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What
symptoms does a patient get when an aneurysm is present?
The most serious symptoms occur when the aneurysm leaks (ruptures). When
an aneurysm leaks, the patient experiences the abrupt onset of the worst
headache of their life. This headache is usually accompanied by nausea,
vomiting, neck stiffness, and light sensitivity. The headache can last
up to two weeks. Hemorrhage may produce only headache or it may progress
to death. Should this type of headache occur, one should call 911 and
be taken immediately to a hospital emergency room.
Sometimes an aneurysm can grow and put pressure on a nerve (cranial nerve)
which may cause eye pain associated with double vision, light sensitivity,
and drooping of the eyelid. Other neurological symptoms such as difficulty
swallowing, walking or trouble thinking may also occur. Aneurysms
may also be discovered by accident during screening for other neurological
problems.
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What
is a subarachnoid hemorrhage?
Subarachnoid hemorrhage is the term used to describe rupture of an aneurysm
into the spinal fluid surrounding the brain and spinal cord. When this
occurs, the chemical effect of the blood on the brain and surrounding
structures causes pain and the other symptoms described above. Other causes
of subarachnoid hemorrhage include hypertension (high blood pressure),
head injury, strokes, or arteriovenous malformations (AVMs).
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How
are aneurysms diagnosed?
Aneurysms usually do not cause symptoms unless they rupture (leak). When
an aneurysm ruptures, the symptoms described above occur. These symptoms
are so characteristic for subarachnoid hemorrhage that often the diagnosis
can be made on this history alone. After the patient arrives in the emergency
room, a CT scan or spinal tap is done which confirms the presence of blood
in the spinal fluid surrounding the brain. An arteriogram (angiogram)
is performed to demonstrate the source of the hemorrhage. An arteriogram
is done by placing a needle into an artery in the groin and running a
catheter (a small, soft, tube) up the artery to the arteries going to
the brain and injecting dye. This dye outlines the inside of the blood
vessels. Up to 20% of the time, the arteriogram may fail to show the source
of the hemorrhage. There is a slight risk of hemorrhage into the groin
or even stroke associated with this test. A magnetic resonance angiogram
(MRA) or computerized tomographic angiogram (CTA) can be done to look
at the arteries and veins with less risk than a formal arteriogram but
is not as accurate. The arteriogram is still the most accurate test.
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What
is the treatment for an aneurysm?
The standard and most effective treatment for an aneurysm is surgical
exposure and placement of a specialized metal clip across the base of
the aneurysm to reform normal vessel and close off the aneurysm. Patients
with a ruptured aneurysm are treated as soon as practically possible in
most cases, to prevent the aneurysm from rupturing again.
A
new treatment consists of placing platinum (GDC) coils into the aneurysm
by an angiographic approach is available for aneurysms of certain shapes.
The long-term durability is not currently known. Follow up with subsequent
arteriograms is necessary to ensure that the aneurysm remains occluded.
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What
other problems can occur after an aneurysm ruptures?
Blood in the spinal fluid after an aneurysm ruptures is irritating to
the outside of the arteries and can cause spasm or narrowing of the arteries.
This may produce a decrease in blood flow going to the brain and can result
in a stroke. Normal treatment for this vasospasm is to give the patient
plenty of 1V fluids and maintain a good blood pressure. Medicine (called
a calcium channel blocker) is also given to reduce the effect of spasm.
If this treatment fails, another type of medicine (Papaverine) can be
injected directly into the arteries of the brain to relieve the spasm
temporarily. Also, a tiny balloon may be inflated inside the narrowed
blood vessels to expand (dilate) them back to the normal size. When hemorrhage
occurs, it can also slow or stop the flow of spinal fluid around the brain.
If this happens, pressure builds up in the brain. This is called hydrocephalus.
This pressure may cause the patient to become sleepy or go into a coma.
It is treated by placing a small hole in the skull and inserting a soft
tube into the central cavities in the brain where the spinal fluid is
made. This alleviates the pressure from the excess fluid.
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What
is the prognosis if one has an aneurysm rupture?
Approximately 50% of patients who suffer from rupture of an aneurysm die
immediately or at some time during the course of their treatment. The
befter the neurological condition initially after the hemorrhage, the
better the prognosis for a satisfactory recovery. Elderly patients often
do worse than younger patients. Aneurysms in certain locations are treated
more easily than in other locations.
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